, in order to prevent inherited mitochondrial disease and infertility treatment . GM techniques that are under consideration include the manipulation of the mitochondrial level , to replace or increase the mutated rDNA , and research methods that could create a baby with three parents , which have already been discussed . The FDA has stated that it is aware of the need to consider a number of ethical and social issues related to these experiments and despite the fact that 44 countries have banned this type of genetic manipulation , the FDA does not want to discuss whether to clinical trials on humans in general be carried out , for them the debate superfluous . Rather than debate the ethics of this procedure , they are the latest conference decided to show how GM should look like children . Participants in the meeting will deliberate about which animals and " in vitro " studies ( tests that are performed outside of a living organism ) will be required prior to experimentation with humans , and the potential risks to research participants as well as for " the children resulting from such research ." For now, the desired genetic results to be focused on the prevention of inherited mitochondrial diseases ( eg LHone ) or infertility , which depend on the quality and quantity of mitochondria in the female egg - although there is no scientific consensus on how important mitochondrial factors for female infertility . Mitochondria are the source of cellular energy . They have their own DNA ( mtDNA ) , which is prone to mutation of DNA jezgrinog . Accumulation mitohondričkih mutation may contribute to faster aging , creating cancer and metabolic diseases . Some mutations in mtDNA can be a trigger for mitochondrial diseases that can be transmitted from mother to child ( but not the father of the child ) . Given the large number of factors , it is very difficult to predict how long it will be a sick child from the mother's mitochondrial mutations . They can even be asymptomatic .
One document above mentioned agencies makes it clear that the potential pitfalls of clinical research in order to create the GM people . The first is sex selection - because the female children created from mitochondrial manipulation could still carry the mutated DNA . It is very possible that because the researchers chose only male embryos . Another pitfall is the idea of a child with three parents - FDA discusses the creation of embryos with three parents , in which the mutated mtDNA from mothers no. 1 is replaced with healthy mtDNA from mothers no. 2 ( which then , through " in vitro " fertilization rates with dad's sperm ) .
This type of experiment could be the trigger for a series of major problems ( very likely through epigenetic changes ) , which may not be visible to the developing fetus . A third potential problem are just dangerous epigenetic changes . Epigenetičari study how external influences ( eg environmental factors ) could affect the genes . Studies show that techniques such as manipulation of mtDNA can cause unpredictable epigenetic changes in the embryo , which could result in birth defects .
There is also the problem that even the FDA admits , and that is that it might be impossible to detect the genetic modification affect the child until it is born . Just remember the movie " Gattaca " - it's easy to see how the concept of GM people could go out of control . In addition to sex selection , clearly concludes that this technology could be used for genetic design of children with certain desirable physical and mental health characteristics .
One thing that is not mentioned in the above document, the agency is a risk that in a near future, the research could introduce genetic material not of human origin . The mere possibility sounds scary .
The Daily Mail , on the other hand revealed that the 01.03.2014 . born first genetically modified babies in the United States , and that the expected birth of 29 more of these babies in the next few months . This news is so shocking , especially if you are known to have babies of which we speak are made with the help of three parents , which again points to all possible moral and ethical ambiguities . All babies are created at the Center for Reproductive Medicine and Science " St Barnabas ' in New Jersey , so it seems that the FDA somewhat lags behind actual events in the U.S. , although the agency would first have to create laws and regulations on the creation of GMOs children, only after that would eventually allowed to create such a baby .
If you think this is the worst that can happen , we recall the statement by Dr. Jacques Cohen, who last year created a storm terrified reaction of fellow scientists and the public because he admitted that he developed a technique with which men can have children of their own , without genetic mixing with women he is ready to start creating human clones .
We are sure that such shocking news to be more , and we doubt that anyone cares about the ethical aspects of research and in terms of earning large amounts of money and scientific prestige .
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